ObjectiveTo evaluate the combination of pembrolizumab, cisplatin and gemcitabine in recurrent platinum-resistant ovarian cancer.MethodsPatients received six cycles of chemotherapy with gemcitabine and cisplatin on day 1 and day 8 of a 21-day treatment cycle.Pembrolizumab was administered on day 1 of cycles 3-6 and as maintenance monotherapy in cycl
Theodor H Lippert,1 Hans-Jörg Sublimug Ruoff,1 Manfred Volm2 1Medical Faculty, University of Tübingen, Tübingen, Germany; 2Medical Faculty, University of Heidelberg, Heidelberg, Germany Abstract: Clinical practice guidelines are indispensable for such a variable disease as malignant solid tumors, with the complex possibilities of dru
Plants experiencing salt stress often exhibit an ionic homeostasis disorder as a primary symptom.Transcription factor OsMYBc positively regulates OsHKT1;1 to control Na+ accumulation in rice shoots.In this study, root tissues from a T-DNA insert mutant of osmybcc-1 (also known as OsMYBc) and its wild type were analyzed using proteomic methods after
In this paper, the new kind of adaptive signal-dependent LMS L-filter for suppression of a 3 Pack Socks mixed noise in greyscale images is developed.It is based on the texture parameter measurement as modification of spatial impulse detector structure.Moreover, the one of GLCM (Gray Level Co-occurrence Matrix) features, namely, the contrast or iner